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Monday, December 29, 2014

Top 10 Jackson Laboratory news stories of 2014

Connecticut Governor Dannel Malloy, National Human Genome Research Institute Director Eric Green, M.D., Ph.D., and other leaders of the academic and scientific worlds joined JAX officials at Oct. 7 dedication ceremony for The Jackson Laboratory for Genomic Medicine in Farmington, Conn.
On Oct. 26, The Jackson Laboratory announced the largest private gift in its history: a $5 million gift from the technology investor David Roux and his wife Barbara, triggering $5 million in matching funds for a total gift of $10 million. The funds will initiate the creation of the Roux Family Center for Genomics and Computational Biology.
A research team led by JAX Professor and Howard Hughes Investigator Susan Ackerman, Ph.D., has
pinpointed a surprising mechanism behind neurodegeneration in mice, one that involves a defect in a key component of the cellular machinery that makes proteins, known as transfer RNA or tRNA. This year the Ackerman lab also reported on a new mechanism involved in misfolded proteins implicated in certain heart diseases.
Maine voters resoundingly approved a bond issue on the Nov. 4 ballot that will enable The Jackson Laboratory to apply for $10 million to fund creation of asophisticated Center for Biometric Analysis on its campus in Bar Harbor, to house state-of-the-art imaging, neurocognitive, metabolomics and physiologic sensing technologies. An additional $1 million pledge from the Connie Cogswell Rossi Foundation will fund a Neurobehavioral Biometry Center within the new facility.
The laboratory of JAX Professor and Howard Hughes Medical Investigator Simon W.M. John, Ph.D., led an exhaustive exploration of an eye structure known as Schlemm’s canal, a key gatekeeper for the proper flow of eye fluid, presenting a number of insights relevant to glaucoma and other diseases.
The Jackson Laboratory Cancer Center has once again earned the renewal of its Cancer Center Support Grant from the National Cancer Institute (NCI). JAX was the first mammalian genetics research institution to be designated a Cancer Center, in 1983, to conduct basic research.
Internationally recognized clinical oncologist and cancer immunologist A. Karolina Palucka, M.D., Ph.D., joined The Jackson Laboratory for Genomic Medicine faculty as professor and associate director of cancer immunology.  In 2014 immunologist and HIV expert Derya Unutmaz, M.D., and Adam Williams, Ph.D., a scientist who studies immune cell function with respect to treating asthma, also joined the growing JAX immunology team as professor and assistant professor, respectively. Other assistant professors recruited in 2014 are neurobiologist Vivek Kumar, Ph.D., and developmental biologists Ewelina Bolcun-Filas, Ph.D., andBasile Tarchini, Ph.D.
In a collaboration that will encompass a broad range of activities to advance cancer research and patient care and accelerate personalized genomic medicine, The Jackson Laboratory and Beth Israel Deaconess Medical Center have established a new academic, research and service relationship. This year the Laboratory alsopartnered with UC Davis on shared research infrastructure and education initiatives and launched a collaborative project with Yale University to develop new mouse models for cancer.
The American Society of Human Genetics and The Jackson Laboratory announced a formal collaboration under which the two organizations will produce and deliver high-quality educational programs to integrate genetic and genomic advances into healthcare. The Laboratory’s clinical and continuing education group also launched three new training programs to help health care providers integrate genetics and genomics into clinical care. 

Retired Jackson Laboratory scientist, environmentalist and philanthropist Douglas Coleman, Ph.D., whose elegantly simple approach to addressing complex biological problems earned him scientific renown and many international prizes, died at his home in Lamoine, Maine, on April 16.

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